PROTOCOL FOR A MULTI-CENTRE RANDOMISED CONTROLLED TRIAL COMPARING ARTHROSCOPIC HIP SURGERY TO PHYSIOTHERAPY-LED CARE FOR FEMOROACETABULAR IMPINGEMENT (FAI): THE AUSTRALIAN FASHION TRIAL

Protocol for a multi-centre randomised controlled trial comparing arthroscopic hip surgery to physiotherapy-led care for femoroacetabular impingement (FAI): the Australian FASHIoN trial

Abstract Background Femoroacetabular impingement syndrome (FAI), a hip disorder affecting active young adults, is believed to be a leading cause of hip osteoarthritis (OA).Current management approaches for FAI include arthroscopic hip surgery and physiotherapy-led non-surgical care; however, there is a paucity of clinical trial evidence comparing t

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Higher efficacy and reduced adverse reactions in neoadjuvant chemotherapy for breast cancer by using pegylated liposomal doxorubicin compared with pirarubicin

Abstract The present study aimed to investigate the efficacy and toxicity of pegylated liposomal doxorubicin (PLD) in preoperative neoadjuvant chemotherapy for patients with breast cancer by comparing with conventional anthracycline.This study is a non-randomized controlled trial.Prospective analysis was conducted after matching as required.A total

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Viral Encephalopathy and Retinopathy in groupers (Epinephelus spp.) in southern Italy: a threat for wild endangered species?

Abstract Background Betanodaviruses are the causative agents of Viral Encephalopathy and Retinopathy (VER).To date, more than 50 species have proved to be susceptible and among them, those found in genus Epinephelus are highly represented.Clinical disease outbreaks are generally characterized by typical nervous signs and significant mortalities mai

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Bioinformatics analysis based on extracted ingredients combined with network pharmacology, molecular docking and molecular dynamics simulation to explore the mechanism of Jinbei oral liquid in the therapy of idiopathic pulmonary fibrosis

Objective: Jinbei oral liquid (JBOL), which is derived from a traditional hospital preparation, is frequently Crystal Mid Rise Relaxed Short utilized to treat idiopathic pulmonary fibrosis (IPF) and has shown efficacy in clinical therapy.However, there are now several obstacles facing the mechanism inquiry, including target proteins, active compone

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Bilateral herpes simplex virus-related peripheral ulcerative keratitis leading to corneal perforation in a patient with primary herpes simplex virus infection

Purpose: To present a case of bilateral peripheral ulcerative keratitis (PUK) caused by primary Furniture Polish herpes simplex virus-1 (HSV-1) infection resulting in corneal perforation.Case Report: A 24-year-old man presented at the eye casualty of our clinic, with a 20-day history of severe pain, redness, photophobia, and tearing in both of his

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